Sunday, February 13, 2005

the nytimes has something that took my eyes off what i was doing:
City health officials announced on Friday that they had detected the rare strain of H.I.V. in one man whose case they described as particularly worrisome because it merged two unusual features: resistance to nearly all anti-retroviral drugs used to treat the infection, and stunningly swift progression from infection to full-fledged AIDS. Scientists say that only with more testing will they hope to determine how virulent the strain is and how specific to this one man its effects are.

That combination drug resistance and rapid AIDS onset, the officials said, could signal a new, more menacing kind of infection, and its discovery set in motion an anxious search by city workers to find the man's sexual partners and have them tested.

The infected man, gay and in his 40's, tested negative for H.I.V. in May 2003, then tested positive last December, health officials said. Investigators believe he may have contracted the virus in October when he engaged in unprotected anal sex with multiple partners while using crystal methamphetamine. By last month, it was clear that three of the four classes of anti-retroviral drugs used against H.I.V. were not working in this case, and the man showed signs of AIDS, including rapid weight loss, a high level of the virus in his bloodstream, and a depleted supply of crucial immune system cells.

Even though the anti-retroviral "cocktail" has extended many lives, some infected people still deteriorate and end up with AIDS, but that process usually takes many years. Doctors say that for a patient to reach that stage in a matter of months is extremely troubling.

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